דלג על פקודות של רצועת הכלים
דלג לתוכן ראשי
 
 

 

 
Dr. Irit Weissman-Fogel 
Office Telephone Number: (972) 48288398
Fax Number: (972) 48288140
Electronic Address: ifogel@univ.haifa.ac.il
 
Research Areas
My primary area of research is pain. My approach throughout the years has been multifaceted, investigating a wide range of mechanisms underlying pain and treatment of pain using advanced neurophysiological methods and psychophysical measurements. In my lab I study brain functions in relation to pain by combining brain imaging (magnetic resonance imaging (MRI)) and electrophysiological techniques (electroencephalography (EEG), evoked potentials and trans-cranial magnetic stimulation (TMS)).   I am using the above mentioned technologies to explore activity patterns and neuro-anatomical changes in the brain of patients with clinical pain conditions and comprehend the interaction between pain, cognition and emotions in chronic pain. Additionally, I study brain mechanisms that subserve and regulate pain in the healthy state in order to identify alterations in mechanisms supporting pain modulation in chronic pain disorders including their therapeutic relevance. The development of better diagnosis and treatment of pain is currently hampered by incomplete understanding of individual differences in pain and the impact that they have on pain treatment is particularly limited.  Toward this aim I am studying the role individual differences in brain morphology and neurophysiology in the prediction of treatment success.
 
Education 
 
B.Sc in Physiotherapy (BPT) - 1985-1989: University of Tel-Aviv, Department of Physiotherapy, Sackler School of Medicine, Tel Aviv, Israel
 
M.Sc in Medical Sciences  - 1997- 200: Technion – Israel Institute of Technology, Faculty of Medicine Haifa, Israel
 
Ph.D. in Clinical Neurophysiology -  2001- 2006: Technion – Israel Institute of Technology, Faculty of Medicine Haifa, Israel
 
Post-Doctoral Studies -  2007-2009: Toronto  Western Research Institute, University Health Network and University of Toronto, Brain, Imaging and Behaviour-Systems Neuroscience,
 
  
Academic Ranks
 
2000-2005:  Teaching Assistant
2005-2007:  Instructor
2009- 2014:  Lecturer
2014- present:  Assistant professor
 
   
Publications
    
1.  Dvir, Z., Shklar, A., Halperin, N., Robinson, D., Weissman, I., Ben- Shoshan, I. (1990) Concentric and eccentric torque variations of the quadriceps in  patellofemoral pain syndrome. Clinical biomechanics, 5:68-72.
 
2.  Weissman-Fogel, I., Sprecher, E., Granovsky, Y., Yarnitsky, D. (2003) Repeated noxious stimulation of the skin enhances cutaneous pain perception of migraine patients in- between attacks: Clinical evidence for continuous subthreshold increase in membrane excitability of central trigeminovascular neurons. Pain, 104:693-700.
 
3.  Granot, M., Weissman-Fogel, I., Crispel, Y., Pud, D., Granovsky, Y., Sprecher, E., Yarnitsky, D. (2008) Determinants of endogenous analgesia extent by diffuse noxious inhibitory control (DNIC) paradigm: do conditioning stimulus painfulness, gender and personality variables matter? Pain, 136:142-9.
 
4.  Weissman-Fogel, I., Sprecher, E., Pud, D. (2008) Effects of catastrophizing on pain  perception and pain modulation. Experimental Brain Research, 186(1):79-85.
 
5.  Weissman-Fogel, I., Dashkovsky, A., Rogowski, Z., Yarnitsky, D. (2008) Vagal  damage  enhances polyneuropathy pain: Additive effect of two algogenic mechanisms. Pain, 138:153-62.
 
6.  Weissman-Fogel, I., Dashkovsky, A., Rogowski, Z., Yarnitsky, D. (2008) An animal model of chemotherapy-induced vagal neuropathy. Muscle & Nerve, 38(6):1634-37.
 
7.  Weissman-Fogel, I., Granovsky, Y., Crispel, Y., Ben-Nun, A., Best, L.A., Yarnitsky, D., Granot, M. (2009) Enhanced pre-surgical pain temporal summation response predicts post-thoracotomy pain intensity during the acute postoperative phase. Journal of Pain, 10(6):628-36.
  
8. Moyedi, M., Weissman-Fogel, I. (2009) Is the insula is "how much" intensity coder? Journal of Neurophysiology, 102(3):1345-7.
 
9. Weissman-Fogel, I., Moayadi, M., Taylor, S.K., Pop, G., Davis, K.D. (2010) Cognitive and Dafault-Mode Resting State Networks: Do Male and Female "Rest" Differently? Human Brain Mapping, 31(11):1713-26.
 
10. Weissman-Fogel, I., Moayedi, M., Tenenbaum, H.C., Goldberg, M.B., Davis, K.D. (2011) Abnormal cortical activity in patients with temporomandibular disorder evoked by cognitive and emotional tasks. Pain, 152(2):384-96.
 
11. Moayadi, M., Weissman-Fogel, I., Crawley, A.P., Goldberg, M.B., Freeman, B.V., Tenenbaum, H.C., Davis, K.D. (2011) Contribution of chronic pain and neuroticism to abnormal forebrain gray matter in patients with temporomandibular disorder. Neuroimage, 55(1):277-86.
 
12. Weissman-Fogel, I., Brayer-Tsvi, N., Defrin, R. (2012) The resolution of the pain system as evaluated with psychophysical testing reveals a proximal to distal gradient of improvement. Experimental Brain Research, 216(2):181-90.
 
13. Granot, M., Weissman-Fogel, I. (2012) Effect of post-surgical neuroplasticity on systemic pain perception: A psychophysical study. European Journal of Pain, 16(2):247-55.
 
14. Salomons, T.V., Moayedi, M., Weissman-Fogel, I., Goldberg, M.B., Freeman, B.V., Tenenbaum, H.C., Davis, K.D. (2012) Perceived Helplessness is Associated with Individual Differences in the Cerebral Motor Output System. European Journal of Neuroscience, 35(9):1481-7.
 
15. Moayedi, M., Weissman-Fogel, I., Salomons, T.V., Crawley, A.P., Goldberg, M.B., Freeman, B.V., Tenenbaum, H.C., Davis, K.D. (2012) Abnormal gray matter aging in chronic pain patients. Brain Research, 25;1456: 82-93.
 
16. Kucyi, A, Moayedi, M., Weissman-Fogel, I., Hodaie, M., Davis, K.D. (2012) Hemispheric asymmetry in white matter connectivity of the temporoparietal junction with the insula and prefrontal cortex. PLoS One 7(4):e35589.
 
17. Moayadi, M., Weissman-Fogel, I., Taylor, K., Salomons, T., Crawley, A.P., Goldberg, M.B., Freeman, B.V., Tenenbaum, H.C., and Davis, K.D. (2012) White matter brain and trigeminal nerve abnormalities in temporomandibular disorder. Pain 153(7):1467-77.
 
18. Nahman-Averbuc, H., Granovsky, Y., Coghill, R.C., Yarnitsky, D., Sprecher, E., Weissman-Fogel, I. (2013 ) Waning of ‘conditioned pain modulation’ over time: A novel manifestation of pro-nociceptiion in migraine. Headache 53(7):1104-15.
 
19. Honigman, L., Yarnitsky, D., Sprecher, E., Weissman-Fogel, I. (2013)  Interrelations between conditioned pain modulation and offset analgesia paradigms. Experimental Brain Research 228(4):493-501.
 
20. Bar-Shalita, T., Vatine, J.J, Parush, S., Yarnitsky, D., Weissman-Fogel, I. (2013) Between-subjects variances in pain perception: testing temporal summation in individuals with sensory modulation disorder. Experimental Brain Research 232(2):587-95.
 
21. Emerson, N.M., Zeidan, F., Lobanov, O.V., Hadsel, M0S., Martucci, K.T., Quevedo, A.S., Starr, C.J., Nahman-Averbuch, H., 21. Emerson, N.M., Zeidan, F., Lobanov, O.V., Hadsel, M0S., Martucci, K.T., Quevedo, A.S., Starr, C.J., Nahman-Averbuch, H., Weissman-Fogel, I., Granovsky, Y., Yarnitsky, D., Coghill, R.C. (2014) Pain Sensitivity is Inversely Related to Regional Grey Matter Density in the Brain. Pain 155(3):566-73.
 
22. Kucyi, A., Moayedi, M., 22. Kucyi, A., Moayedi, M., Weissman-Fogel, I., Goldberg, M.B., Freeman, B.V., Tenenbaum, H.C., Davis, K.D. (2014) Enhanced medial prefrontal-default mode network functional connectivity in chronic pain and its association with  pain rumination. Journal of Neuroscience 34(11):3969-75.
 
23. Kodesh, E., Weissman-Fogel, I. (2014) Exercise-induced hypoalgesia - interval versus continuous mode.  Applied physiology, nutrition, and metabolism  39(7):829-34. Editors’ Choice (Health Selections)
 
24. Weissman-Fogel, I., Dror, A., Defrin, R. (2014) Temporal and spatial aspects of experimental tonic pain: Understanding pain adaptation and intensification. European Journal of Pain doi: 10.1002/ejp.562. [Epub ahead of print]
 
25. Nahman-Averbuch, H., Martucci, K.T., Granovsky, Y., 25. Nahman-Averbuch, H., Martucci, K.T., Granovsky, Y., Weissman-Fogel, I., Yarnitsky, D., Coghill R.C. (2014) Distinct brain mechanisms support spatial vs temporal filtering of nociceptive information. Pain 155(12):2491-501.